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428 open federal grants for nonprofits

Federal grant opportunities on Grants.gov open to 501(c)(3) and other nonprofit organizations, still open, soonest deadline first.

Updated Oct 18, 2026 · source: Grants.gov
National Institutes of Health

Limited Competition: Small Grant Program for the NCATS Clinical and Translational Science Award (CTSA) Program (R03 Clinical Trial Optional)

PAR-25-155 · Up to $50K

National Institutes of Health

Community Engagement Evaluation and Data Coordination (CEED) Hub to Advance Data and Practice Transformation for Optimizing Oral Health for All (U01, Clinical Trial Not Allowed)

RFA-DE-27-001 · $1M total program funding

National Institutes of Health

Sustained Support for Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

RFA-CA-27-021 · Up to $600K

National Institutes of Health

Advanced Development of Informatics Technologies for Cancer Research and Management (U24 Clinical Trial Optional)

RFA-CA-27-020 · Up to $600K

National Institutes of Health

PRIMED-AI: Data-to-Model Academic-Industrial Partnerships (D2M-AIP) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (UG3/UH3 Clinical Trial Optional)

RFA-RM-27-012

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National Institutes of Health

Model-to-Clinic (M2C) for Precision Medicine with AI: Integrating Imaging with Multimodal Data (PRIMED-AI) (UG3/UH3, Clinical Trial Optional)

RFA-RM-27-013

Animal and Plant Health Inspection Service

Plant Protection Act Section 7721 Fiscal Year 2027 National Clean Plant Network (NCPN)

USDA-APHIS-10031-PPQ-NCPN-2027 · Up to $3.5M

Health Resources and Services Administration

Fiscal Year (FY) 2027 Service Area Competition (SAC)

HRSA-27-005 · Up to $10.1M

National Institutes of Health

Nutrition Obesity Research Centers (NORCs) (P30 Clinical Trial Optional)

RFA-DK-27-120 · Up to $750K

Bureau of Justice Assistance

BJA FY 2026 Tribal Justice Training and Technical Assistance Program

O-BJA-2026-172727 · Up to $1.9M

National Institutes of Health

Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)

RFA-MH-27-140 · $1.5M total program funding

Centers for Disease Control - NCBDDD

Long-term health outcomes of people living with spina bifida

CDC-RFA-DD-26-0222 · Up to $300K

Office of Juvenile Justice Delinquency Prevention

OJJDP FY 2026 Victims of Child Abuse Act Training and Technical Assistance for Child Abuse Professionals

O-OJJDP-2026-172755 · Up to $2.9M

Office of Juvenile Justice Delinquency Prevention

OJJDP FY 2026 Missing and Exploited Children Training and Technical Assistance

O-OJJDP-2026-172744 · Up to $1.2M

Office of Juvenile Justice Delinquency Prevention

OJJDP FY 2026 Strengthening Internet Crimes Against Children (ICAC) Technological Investigative Capacity

O-OJJDP-2026-172753 · Up to $675K

Office of Juvenile Justice Delinquency Prevention

OJJDP FY 2026 Multistate Mentoring Programs

O-OJJDP-2026-172745 · Up to $4M

Office of Juvenile Justice Delinquency Prevention

OJJDP FY 2026 Community and Schools Youth Drug Prevention Program

O-OJJDP-2026-172734 · Up to $750K

National Institutes of Health

GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

RFA-HG-27-012 · Up to $2.3M

National Institutes of Health

GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)

RFA-HG-27-011 · Up to $1.3M

Bureau of Justice Assistance

BJA FY 2026 Students, Teachers, and Officers Preventing (STOP) School Violence Program

O-BJA-2026-172709 · Up to $2M

Bureau of Justice Assistance

BJA FY 2026 Second Chance Act Community-based Reentry Program

O-BJA-2026-172717 · Up to $1M

69A350 OSDBU

Small Business Transportation Technical Assistance Center (Region 3)

OST-OSDBU-2027-SBTTAC-REGION3-FY2027-1 · Up to $231K · Cost share required

69A350 OSDBU

Small Business Transportation Technical Assistance Center (Region 1)

OST-OSDBU-2027-SBTTAC-REGION1-FY2027-1 · Up to $377K · Cost share required

69A350 OSDBU

Region 4 Small Business Transportation Technical Assistance Center (SBTTAC)

OST-OSDBU-2027-SBTTAC-REGION-4-FY2027-1 · Up to $250K

National Institutes of Health

Clinical Observational (CO) Studies in Musculoskeletal, Rheumatic, and Skin Diseases (R01 Clinical Trial Not Allowed)

PAR-24-280

National Institutes of Health

Exploratory Clinical Trial Grants in Arthritis and Musculoskeletal and Skin Diseases (R61 Clinical Trial Required)

PAR-24-279

Bureau of Justice Assistance

BJA FY 2026 Upholding the Rule of Law and Preventing Wrongful Convictions Program

O-BJA-2026-172726 · Up to $600K

Bureau of Justice Assistance

BJA FY 2026 Comprehensive Opioid, Stimulant, and Substance Use Program (COSSUP) Training and Technical Assistance (TTA)

O-BJA-2026-172724 · Up to $2M

Office of Juvenile Justice Delinquency Prevention

OJJDP FY 2026 Second Chance Act Youth Reentry Program

O-OJJDP-2026-172751 · Up to $750K

Office of Juvenile Justice Delinquency Prevention

OJJDP FY 2026 Internet Crimes Against Children (ICAC) Task Force Program Support

O-OJJDP-2026-172731 · Up to $1.2M

National Park Service

Exploring and Enhancing Outdoor and Heritage Tourism in the Chesapeake Bay Watershed

P27AS00032 · Up to $50K

National Institutes of Health

Developing novel theory and methods for understanding the genetic architecture of complex human traits (R01 Clinical Trial Not Allowed)

PAR-25-255

Centers for Disease Control and Prevention - ERA

Emerging Infections Network - Research for Preventing, Detecting, and Managing Travel-associated Infectious Diseases

RFA-CK-26-035 · Up to $6M

Centers for Disease Control and Prevention - ERA

US Travelers Health Research, Surveillance, Communication, and Outreach Network

RFA-CK-26-036 · Up to $1M

National Institutes of Health

Secondary Analysis and Integration of Existing Data to Elucidate Cancer Risk and Related Outcomes (R01 Clinical Trial Not Allowed)

PAR-25-095 · Up to $350K

Showing the 40 soonest deadlines of 428. Search all on Grants.gov.

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